Probiotics are popular for dogs with digestive upset. Purina Pro Plan Veterinary Diets FortiFlora is one of the most recommended by vets. This review looks at what it contains, what research says and how to use it.
Verdict at a Glance: FortiFlora is a widely recommended probiotic with a specific, studied strain. Many vets use it for dogs with diarrhea or digestive upset. It’s easy to give and most dogs like the taste. It doesn’t replace a vet exam when diarrhea is severe or lasts more than a day or two.
At a Glance
| Feature | Details |
|---|---|
| Type | Probiotic supplement |
| Strain | Enterococcus faecium SF68 |
| Form | Powder sachets sprinkled on food (chews also available; check current range) |
| Dosing | Typically one sachet daily (check label) |
| Maker | Purina Pro Plan Veterinary Diets |
What It Is and How It Works
FortiFlora contains a specific probiotic strain, Enterococcus faecium SF68. Studies in dogs and cats have looked at this strain for diarrhea, including in shelter settings.
Each sachet also contains added vitamins and antioxidants, and it’s flavored to be palatable, so most dogs eat it readily sprinkled on food. That makes it easier to give than many capsules or tablets.
Vets commonly suggest probiotics for mild diarrhea, stress-related stomach upset such as boarding or travel, diet changes and during antibiotic courses. Probiotics work best given consistently each day. Benefits can fade after stopping, since most probiotic bacteria don’t permanently settle in the gut.
Probiotic quality varies widely. Some products contain fewer live organisms than claimed. Choosing a product from a reputable company with studied strains helps. See diarrhea in dogs and dog diarrhea: here’s what you should do.
Pros and Cons
| Pros | Cons |
|---|---|
| Studied probiotic strain | Cost adds up with daily use |
| Easy to give | Not a fix for serious illness |
| Most dogs like the taste | Contains animal digest flavoring |
| Widely recommended by vets | Evidence for some uses is limited |
| Single-dose sachets |
When Diarrhea Needs a Vet
Mild diarrhea in an otherwise bright dog often settles within a day or two. Call your vet promptly if:
- Diarrhea lasts more than a day or two
- There’s blood in the stool or black, tarry stool
- Your dog is vomiting as well
- Your dog seems lethargic, weak or in pain
- Your dog is a young puppy, senior or has health conditions
- You suspect your dog ate something toxic or a foreign object
Puppies can become dehydrated quickly, and some causes of diarrhea, such as parvovirus, are serious.
Safety Notes and Possible Side Effects
- Most dogs tolerate it well.
- Mild gas is possible when starting a probiotic.
- Check with your vet if your dog is on a strict diet or has allergies to the flavoring.
- Probiotics don’t replace treatment for serious illness.
Things to Consider Before Buying
- See your vet for diarrhea that lasts or is severe.
- Follow label dosing.
- Store sachets as directed, away from heat and moisture.
- Give it daily for best results.
- Use it alongside your vet’s other advice, such as a bland diet.
Tips for Using It
- Sprinkle on wet food or a small portion of the meal.
- Keep a few sachets on hand for travel or diet changes.
- Track stool quality.
Who It Suits
| Good fit if… | Consider something else if… |
|---|---|
| Your dog has mild digestive upset | Your dog has severe or bloody diarrhea (see your vet) |
| Your vet recommends a probiotic | |
| You’re changing your dog’s diet |
Alternatives to Consider
| Option | How it differs |
|---|---|
| Other veterinary probiotics | Different strains |
| Bland diets | Short-term support |
| Prescription GI diets | For ongoing issues |
When to Call Your Vet
Contact your vet if:
- Diarrhea lasts more than a day or two
- Blood in stool
- Vomiting or lethargy
Frequently Asked Questions
What is FortiFlora used for?
Vets often recommend it for dogs with diarrhea or digestive upset, and sometimes during diet changes or antibiotic courses.
How long does FortiFlora take to work?
Some dogs improve within a few days. Ask your vet how long to give it.
Can I give FortiFlora every day?
Many dogs take it daily. Ask your vet about long-term use.
Does FortiFlora have side effects?
Most dogs tolerate it well. Mild gas is possible.
Can I give FortiFlora with antibiotics?
Many vets recommend probiotics during antibiotics. Ask your vet about timing.
Is FortiFlora safe for puppies?
It’s commonly used in puppies. Puppies with diarrhea should see a vet.
Can cats take FortiFlora?
There’s a separate feline version.
Do I need a prescription?
FortiFlora is often sold through vets, but it doesn’t require a prescription in many places.
Pet Health Man is independent and isn’t paid by the brands we review. Product formulas, specifications and prices change, so check the current label or the manufacturer’s information before you buy.
This article is for general information only and isn’t a substitute for professional veterinary advice. If you’re worried about your pet’s health, contact your veterinarian or an emergency animal hospital.



